Soak gelatin in ¼ cup milk for 5 minutes. (Soaking gelatin in liquid is also called “blooming.”).
Bring remaining milk to a boil. Add dissolved gelatin to boiling milk, stirring.
Turn off heat, stir in cream cheese until melted.
Pour mixture into a mixing bowl.
Whisk in honey, orange juice and vanilla.
Pour ¼ cup into each papaya half.
Refrigerate until set, about 2 hours.
Cover with plastic wrap and let rest overnight.